Impaired Pharmacokinetics of Amiodarone under Veno-Venous Extracorporeal Membrane Oxygenation: From Bench to Bedside

Impaired Pharmacokinetics of Amiodarone under Veno-Venous Extracorporeal Membrane Oxygenation: From Bench to Bedside

Background: Adjusting drug therapy under veno-venous extracorporeal membrane oxygenation (VV ECMO) is challenging. Although impaired pharmacokinetics (PK) under VV ECMO have been reported for sedative drugs and antibiotics, data about amiodarone are lacking. We evaluated the pharmacokinetics of amio...

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Bibliographic Details
Main Authors: Mickaël Lescroart, Claire Pressiat, Benjamin Péquignot, N’Guyen Tran, Jean-Louis Hébert, Nassib Alsagheer, Nicolas Gambier, Bijan Ghaleh, Julien Scala-Bertola, Bruno Levy
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
amiodarone
VV ECMO
pharmacokinetics
Monte-Carlo simulations
Online Access:https://www.mdpi.com/1999-4923/14/5/974

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https://www.mdpi.com/1999-4923/14/5/974

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