Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer

Molecular Interactions Stabilizing the Promatrix Metalloprotease-9·Serglycin Heteromer

Previous studies have shown that THP-1 cells produced an SDS-stable and reduction-sensitive complex between proMMP-9 and a chondroitin sulfate proteoglycan (CSPG) core protein. The complex could be reconstituted in vitro using purified serglycin (SG) and proMMP-9 and contained no inter-disulfide bri...

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Bibliographic Details
Main Authors: Rangita Dawadi, Nabin Malla, Beate Hegge, Imin Wushur, Eli Berg, Gunbjørg Svineng, Ingebrigt Sylte, Jan-Olof Winberg
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
serglycin
proMMP-9
proMMP-9 deletion variants
proMMP-9 complexes
in vitro reconstitution
peptide arrays
Online Access:https://www.mdpi.com/1422-0067/21/12/4205

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https://www.mdpi.com/1422-0067/21/12/4205

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