Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses

Alternative NF-κB Signaling Discriminates Induction of the Tumor Marker Fascin by the Viral Oncoproteins Tax-1 and Tax-2 of Human T-Cell Leukemia Viruses

Transcriptional regulation of the actin-bundling protein and tumor marker Fascin is highly diverse depending on cell and tumor type. Previously, we discovered that the viral oncoprotein Tax-1 of human T-cell leukemia virus type 1 (HTLV-1) considerably enhances Fascin expression in T-cells, depending...

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Bibliographic Details
Main Authors: Stefanie Heym, Caroline F. Mohr, Hanna C. Engelbrecht, Bernhard Fleckenstein, Andrea K. Thoma-Kress
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
Fascin
tumor virus
HTLV-1
human T-cell leukemia virus type 1
alternative NF-κB
viral oncoprotein
Online Access:https://www.mdpi.com/2072-6694/14/3/537

Internet

https://www.mdpi.com/2072-6694/14/3/537

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