Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes.

The incretin effect on insulin secretion was investigated in 8 subjects with type 2 diabetes (T2D) and 8 with normal glucose tolerance (NGT), using 25, 75, and 125 g oral glucose tolerance tests (OGTT) and isoglycemic intravenous glucose infusions (IIGI). The ß-cell response was evaluated using a mo...

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Bibliographic Details
Main Authors: Andrea Mari, Jonatan I Bagger, Ele Ferrannini, Jens J Holst, Filip K Knop, Tina Vilsbøll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3760909?pdf=render