Nontraditional Roles of DNA Polymerase Eta Support Genome Duplication and Stability

DNA polymerase eta (Pol η) is a Y-family polymerase and the product of the <i>POLH</i> gene. Autosomal recessive inheritance of <i>POLH</i> mutations is the cause of the xeroderma pigmentosum variant, a cancer predisposition syndrome. This review summarizes mounting evidence...

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Bibliographic Details
Main Author: Kristin A. Eckert
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/1/175