Transcriptional Profiling of a Cross-Protective Salmonella enterica serovar Typhimurium UK-1 dam Mutant Identifies a Set of Genes More Transcriptionally Active Compared to Wild-Type, and Stably Transcribed across Biologically Relevant Microenvironments

Transcriptional Profiling of a Cross-Protective Salmonella enterica serovar Typhimurium UK-1 dam Mutant Identifies a Set of Genes More Transcriptionally Active Compared to Wild-Type, and Stably Transcribed across Biologically Relevant Microenvironments

Vaccination with Salmonella enterica serovar Typhimurium lacking DNA adenine methyltransferase confers cross-protective immunity against multiple Salmonella serotypes. The mechanistic basis is thought to be associated with the de-repression of genes that are tightly regulated when transiting from on...

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Bibliographic Details
Main Authors: Claire B. Miller, Sebastian Aguilar Pierlé, Kelly A. Brayton, Jennine N. Ochoa, Devendra H. Shah, Kevin K. Lahmers
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Pathogens
Subjects:
Salmonella Typhimurium
DNA adenine methyltransferase
transcriptome
immunity
bacteriophage
fimbriae
Online Access:http://www.mdpi.com/2076-0817/3/2/417

Internet

http://www.mdpi.com/2076-0817/3/2/417

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