Critical Quality Control Methods for a Novel Anticoagulant Candidate LFG-Na by HPSEC-MALLS-RID and Bioactivity Assays

A low molecular weight fucosylated glycosaminoglycan sodium (LFG-Na) is a novel anticoagulant candidate from the sea cucumber <i>Holothuria fuscopunctata</i> that selectively inhibits intrinsic tenase (iXase). The molecular weight, molecular weight distribution and bioactivities are the...

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Bibliographic Details
Main Authors: Shunliang Zheng, Yi Wang, Jiashuo Wu, Siyao Wang, Huaifu Wei, Yongchun Zhang, Jianbo Zhou, Yue Shi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/27/14/4522