Inhibition of Hepatitis B Virus (HBV) by Tachyplesin, a Marine Antimicrobial Cell-Penetrating Peptide

Inhibition of Hepatitis B Virus (HBV) by Tachyplesin, a Marine Antimicrobial Cell-Penetrating Peptide

We investigate the role of Tachyplesin (Tpl), a marine antimicrobial cell-penetrating peptide, as an anti-HBV agent. Our findings, using confocal microscopy and flow cytometry, demonstrate the internalization of FITC-Tpl in both Huh7 and HepG2 cell lines. Further, our results show that Tpl inhibits...

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Bibliographic Details
Main Authors: Pankhuri Narula, Sankar Kiruthika, Shruti Chowdhari, Perumal Vivekanandan, Archana Chugh
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
antimicrobial peptide
antiviral peptide
cell-penetrating peptide
hepatitis B virus Tachyplesin (Tpl)
virion secretion
Online Access:https://www.mdpi.com/1999-4923/15/2/672

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https://www.mdpi.com/1999-4923/15/2/672

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