Ruthenium-Catalyzed Selective Hydrogenation of bis-Arylidene Tetramic Acids. Application to the Synthesis of Novel Structurally Diverse Pyrrolidine-2,4-diones

Ruthenium-Catalyzed Selective Hydrogenation of bis-Arylidene Tetramic Acids. Application to the Synthesis of Novel Structurally Diverse Pyrrolidine-2,4-diones

Catalytic hydrogenation of 3,5-bis-arylidenetetramic acids, known for their biological activity, has been developed. The chemoselective ruthenium-catalyzed reduction of the exocyclic carbon-carbon double bonds on pyrrolidine-2,4-dione ring system, containing other reducible functions, has been inves...

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Bibliographic Details
Main Authors: Olga Igglessi-Markopoulou, John Markopoulos, Dimitris Matiadis, Christos S. Karaiskos
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Molecules
Subjects:
hydrogenation
homogeneous catalysis
ruthenium catalysts
BINAP
arylidenetetramic acid
Online Access:http://www.mdpi.com/1420-3049/16/7/6116/

Internet

http://www.mdpi.com/1420-3049/16/7/6116/

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