Disturbed bone marrow adiposity in patients with Cushing’s syndrome and glucocorticoid- and postmenopausal- induced osteoporosis

Disturbed bone marrow adiposity in patients with Cushing’s syndrome and glucocorticoid- and postmenopausal- induced osteoporosis

BackgroundSkeletal stem/progenitor cells (SSPCs) in the bone marrow can differentiate into osteoblasts or adipocytes in response to microenvironmental signalling input, including hormonal signalling. Glucocorticoids (GC) are corticosteroid hormones that promote adipogenic differentiation and are end...

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Bibliographic Details
Main Authors: Nina N. Sørensen, Christina M. Andreasen, Pia R. Jensen, Ellen M. Hauge, Jens Bollerslev, Jean-Marie Delaissé, Moustapha Kassem, Abbas Jafari, Marta Diaz-delCastillo, Thomas L. Andersen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Endocrinology
Subjects:
bone
bone marrow adipocyte (BMAd)
bone marrow adipose tissue (BMAT)
Cushing´s syndrome
glucocorticoids
osteoporosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1232574/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1232574/full

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