Protective effect of adipose-derived stromal cell-secretome attenuate autophagy induced by liver ischemia–reperfusion and partial hepatectomy

Protective effect of adipose-derived stromal cell-secretome attenuate autophagy induced by liver ischemia–reperfusion and partial hepatectomy

Abstract Background The therapeutic effects of adipose-derived mesenchymal stromal cells (ADSCs) may be mainly mediated by their paracrine effects. The ADSC-secretome can ameliorate hepatic ischemia–reperfusion injury (IRI). We explored the therapeutic effect of the ADSC-secretome from the perspecti...

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Bibliographic Details
Main Authors: Yajun Ma, Zhihui Jiao, Xiaoning Liu, Qianzhen Zhang, Chenxi Piao, Jiayuan Xu, Hongbin Wang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Stem Cell Research & Therapy
Subjects:
ADSC-secretome
Autophagy
IRI
Miniature pig
Laparoscopy
Online Access:https://doi.org/10.1186/s13287-022-03109-2

Internet

https://doi.org/10.1186/s13287-022-03109-2

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