Exogenous laminin exhibits a unique vascular pattern in the brain via binding to dystroglycan and integrins

Abstract Background Unlike other proteins that exhibit a diffusion pattern after intracerebral injection, laminin displays a vascular pattern. It remains unclear if this unique vascular pattern is caused by laminin-receptor interaction or laminin self-assembly. Methods We compared the distribution o...

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Bibliographic Details
Main Authors: Jingsong Ruan, Karen K. McKee, Peter D. Yurchenco, Yao Yao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-022-00396-y