Optimal performance objectives in the highly conserved bone morphogenetic protein signaling pathway

Abstract Throughout development, complex networks of cell signaling pathways drive cellular decision-making across different tissues and contexts. The transforming growth factor β (TGF-β) pathways, including the BMP/Smad pathway, play crucial roles in determining cellular responses. However, as the...

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Bibliographic Details
Main Authors: Razeen Shaikh, Nissa J. Larson, Jayden Kam, Donny Hanjaya-Putra, Jeremiah Zartman, David M. Umulis, Linlin Li, Gregory T. Reeves
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00430-9