Long-term aerobic exercise protects against cisplatin-induced nephrotoxicity by modulating the expression of IL-6 and HO-1.

Long-term aerobic exercise protects against cisplatin-induced nephrotoxicity by modulating the expression of IL-6 and HO-1.

Nephrotoxicity is substantial side effect for 30% of patients undergoing cancer therapy with cisplatin and may force them to change or even abandon the treatment. Studies regarding aerobic exercise have shown its efficacy for the treatment of many types of diseases and its capacity to reduce tumors....

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Bibliographic Details
Main Authors: Mariana Yasue Saito Miyagi, Marilia Seelaender, Angela Castoldi, Danilo Candido de Almeida, Aline Villa Nova Bacurau, Vinicius Andrade-Oliveira, Lucas Maceratesi Enjiu, Marcus Pisciottano, Caroline Yuri Hayashida, Meire Ioshie Hiyane, Patricia Chakur Brum, Niels Olsen Saraiva Camara, Mariane Tami Amano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4182716?pdf=render

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http://europepmc.org/articles/PMC4182716?pdf=render

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