Single-Cell Analysis Differentiates the Effects of p53 Mutation and p53 Loss on Cell Compositions of Oncogenic Kras-Driven Pancreatic Cancer

Single-Cell Analysis Differentiates the Effects of p53 Mutation and p53 Loss on Cell Compositions of Oncogenic Kras-Driven Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignant disease with a dismal prognosis. In the past decades, a plethora of genetically engineered mouse models (GEMMs) with autochthonous pancreatic tumor development have greatly facilitated studies of pancreatic cancer. Commonly used GEMM...

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Bibliographic Details
Main Authors: Xinlei Sun, Daowei Yang, Yang Chen
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
pancreatic cancer
tumor microenvironment
single-cell analysis
Online Access:https://www.mdpi.com/2073-4409/12/22/2614

Internet

https://www.mdpi.com/2073-4409/12/22/2614

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