Unfractionated heparin reverses aspirin inhibition of platelets during coronary artery bypass graft surgery

Abstract Unfractionated heparin (UFH) is an effective antithrombotic during surgery but has known adverse effects, in particular on platelets. A marked increase in platelet responsiveness has previously been observed in patients within minutes of receiving UFH, despite adequate inhibition by aspirin...

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Bibliographic Details
Main Authors: Robert E. Turnbull, Azhar Hafeez, Katrin N. Sander, David A. Barrett, Gavin J. Murphy, Alison H. Goodall
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58005-x