Unfractionated heparin reverses aspirin inhibition of platelets during coronary artery bypass graft surgery
Abstract Unfractionated heparin (UFH) is an effective antithrombotic during surgery but has known adverse effects, in particular on platelets. A marked increase in platelet responsiveness has previously been observed in patients within minutes of receiving UFH, despite adequate inhibition by aspirin...
Main Authors: | Robert E. Turnbull, Azhar Hafeez, Katrin N. Sander, David A. Barrett, Gavin J. Murphy, Alison H. Goodall |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-58005-x |
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