c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

Summary: Corticospinal tract (CST) neurons innervate the deep spinal dorsal horn to sustain chronic neuropathic pain. The majority of neurons targeted by the CST are interneurons expressing the transcription factor c-Maf. Here, we used intersectional genetics to decipher the function of these neuron...

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Bibliographic Details
Main Authors: Noémie Frezel, Matteo Ranucci, Edmund Foster, Hagen Wende, Pawel Pelczar, Raquel Mendes, Robert P. Ganley, Karolina Werynska, Simon d’Aquin, Camilla Beccarini, Carmen Birchmeier, Hanns Ulrich Zeilhofer, Hendrik Wildner
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723003066

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http://www.sciencedirect.com/science/article/pii/S2211124723003066

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