<i>Mycobacterium tuberculosis</i> Infection Induces BCSFB Disruption but No BBB Disruption In Vivo: Implications in the Pathophysiology of Tuberculous Meningitis

<i>Mycobacterium tuberculosis</i> Infection Induces BCSFB Disruption but No BBB Disruption In Vivo: Implications in the Pathophysiology of Tuberculous Meningitis

Central nervous system (CNS) tuberculosis is the most lethal and devastating form among the diseases caused by <i>Mycobacterium tuberculosis</i>. The mechanisms by which <i>M. tuberculosis</i> bacilli enter the CNS are still unclear. However, the BBB and the BCSFB have been p...

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Bibliographic Details
Main Authors: Carlos Sánchez-Garibay, Citlaltepetl Salinas-Lara, Marcos Artemio Gómez-López, Luis O. Soto-Rojas, Nidia Karen Castillón-Benavides, Omar Jorge Castillón-Benavides, María Elena Hernández-Campos, Rogelio Hernández-Pando, Brenda Marquina-Castillo, Manuel Alejandro Flores-Barrada, José Alberto Choreño-Parra, Juan Carlos León-Contreras, Martha Lilia Tena-Suck, Dulce Adriana Mata-Espinosa, Porfirio Nava, Jessica Medina-Mendoza, Cesar Augusto Rodríguez-Balderas
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
tuberculosis
central nervous system
meningitis
blood-brain barrier
blood-cerebrospinal fluid barrier
choroid plexus
Online Access:https://www.mdpi.com/1422-0067/23/12/6436

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https://www.mdpi.com/1422-0067/23/12/6436

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