Cancer evolution is associated with pervasive positive selection on globally expressed genes.
Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires learning the dynamics of the cancer evolutionary process. We present here a large-scale analysis of the dynamics of this evolutionary proces...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-03-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3945297?pdf=render |