Detection of the KIAA1549-BRAF fusion gene in cells forming microvascular proliferations in pilocytic astrocytoma.

Microvascular proliferation (MVP), an aberrant vascular structure containing multilayered mitotically active endothelial- and smooth-muscle cells/pericytes, is a histopathological hallmark of glioblastoma multiforme (GBM). Although MVP tends to be associated with high-grade glioma, it has also been...

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Main Authors: Shinji Yamashita, Hideo Takeshima, Fumitaka Matsumoto, Kouji Yamasaki, Tsuyoshi Fukushima, Hideyuki Sakoda, Masamitsu Nakazato, Kiyotaka Saito, Asako Mizuguchi, Takashi Watanabe, Hajime Ohta, Kiyotaka Yokogami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220146