Nutrient Limitation Inactivates Mrc1-to-Cds1 Checkpoint Signalling in Schizosaccharomyces pombe

Nutrient Limitation Inactivates Mrc1-to-Cds1 Checkpoint Signalling in Schizosaccharomyces pombe

The S. pombe checkpoint kinase, Cds1, protects the integrity of stalled DNA replication forks after its phosphorylation at threonine-11 by Rad3 (ATR). Modified Cds1 associates through its N-terminal forkhead-associated domain (FHA)-domain with Mrc1 (Claspin) at stalled forks. We report here that nut...

Full description

Bibliographic Details
Main Authors:	Jessica Fletcher, Liam Griffiths, Thomas Caspari
Format:	Article
Language:	English
Published:	MDPI AG 2018-02-01
Series:	Cells
Subjects:	replication kinase checkpoint postmitotic fission yeast S. pombe Cds1 starvation glucose nitrogen cell cycle
Online Access:	http://www.mdpi.com/2073-4409/7/2/15

Similar Items

Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe
by: Hokuto Ohtsuka, et al.
Published: (2022-06-01)

S. pombe placed on the prion map
by: Jacqueline Hayles
Published: (2017-02-01)

RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5
by: Kosuke Okazaki, et al.
Published: (2018-06-01)

Analysis of stress-induced duplex destabilization (SIDD) properties of replication origins, genes and intergenes in the fission yeast, <it>Schizosaccharomyces pombe</it>
by: Yadav Mukesh P, et al.
Published: (2012-11-01)

Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4+
by: Nimna S. Ranatunga, et al.
Published: (2016-10-01)

The Combined Use of Schizosaccharomyces pombe and Lachancea thermotolerans—Effect on the Anthocyanin Wine Composition
by: Ángel Benito, et al.
Published: (2017-05-01)

Genome-Wide Characterization of the Phosphate Starvation Response in <it>Schizosaccharomyces pombe</it>
by: Carter-O’Connell Ian, et al.
Published: (2012-12-01)

Characterisation of Schizosaccharomyces pombe α-actinin
by: Barbara Addario, et al.
Published: (2016-03-01)

The effect of magnesium on mitotic spindle formation in Schizosaccharomyces pombe
by: Gulsen Uz, et al.

Analysis of the Localization of <i>Schizosaccharomyces pombe</i> Glucan Synthases in the Presence of the Antifungal Agent Caspofungin
by: Esther San-Quirico, et al.
Published: (2023-02-01)

Single-Agent and Fixed-Dose Combination HIV-1 Protease Inhibitor Drugs in Fission Yeast (<i>Schizosaccharomyces pombe</i>)
by: Jiantao Zhang, et al.
Published: (2021-06-01)

Sib1, Sib2, and Sib3 proteins are required for ferrichrome-mediated cross-feeding interaction between Schizosaccharomyces pombe and Saccharomyces cerevisiae
by: Ariane Brault, et al.
Published: (2022-07-01)

Module-based construction of plasmids for chromosomal integration of the fission yeast Schizosaccharomyces pombe
by: Yasutaka Kakui, et al.
Published: (2015-01-01)

The Effect of ATP Sulphurylase on the Prooxidant Properties of Selenate in Yeast Schizosaccharomyces pombe
by: Štefan Fujs, et al.
Published: (2009-01-01)

Basis for using thioredoxin as an electron donor by Schizosaccharomyces pombe Gpx1 and Tpx1
by: Fawad Ahmad, et al.
Published: (2022-04-01)

Comparative Research: Regulatory Mechanisms of Ribosomal Gene Transcription in <i>Saccharomyces cerevisiae</i> and <i>Schizosaccharomyces pombe</i>
by: Hayato Hirai, et al.
Published: (2023-02-01)

Schizosaccharomyces pombe: A Promising Biotechnology for Modulating Wine Composition
by: Iris Loira, et al.
Published: (2018-08-01)

Genes Controlling 2-deoxyglucose Induced Lysis and Formation of Reactive Oxygen Species in Schizosaccharomyces pombe
by: Akshay Vishwanatha, et al.
Published: (2017-09-01)

Lipids and Trehalose Actively Cooperate in Heat Stress Management of <i>Schizosaccharomyces pombe</i>
by: Mária Péter, et al.
Published: (2021-12-01)

Determination of the efficient enzyme concentration for lytic digestion of vegetative cells but not spores in Schizosaccharomyces pombe
by: Miroslava, et al.
Published: (2017-06-01)

Specific Functional Features of the Cell Integrity MAP Kinase Pathway in the Dimorphic Fission Yeast <i>Schizosaccharomyces japonicus</i>
by: Elisa Gómez-Gil, et al.
Published: (2021-06-01)

FUNCTIONAL CHARACTERIZATION OF SPERMINE FAMILY TRANSPORTER caf5+ IN Schizosaccharomyces pombe (Lindner)
by: Aslıhan Örs Gevrekci
Published: (2019-10-01)

Glucose to lactate shift reprograms CDK-dependent mitotic decisions and its communication with MAPK Sty1 in Schizosaccharomyces pombe
by: Priyanka Sarkar, et al.
Published: (2023-10-01)

Genome wide transcription profiling of the effects of overexpression of Spc1 and its kinase dead mutant in Schizosaccharomyces pombe
by: Madhurima Paul, et al.
Published: (2015-12-01)

Fission Yeast Methylenetetrahydrofolate Reductase Ensures Mitotic and Meiotic Chromosome Segregation Fidelity
by: Kim Kiat Lim, et al.
Published: (2021-01-01)

Suppressor Analysis Uncovers That MAPs and Microtubule Dynamics Balance with the Cut7/Kinesin-5 Motor for Mitotic Spindle Assembly in Schizosaccharomyces pombe
by: Masashi Yukawa, et al.
Published: (2019-01-01)

Rice (<i>Oryza sativa</i>) TIR1 and 5′adamantyl-IAA Significantly Improve the Auxin-Inducible Degron System in <i>Schizosaccharomyces pombe</i>
by: Adam T. Watson, et al.
Published: (2021-06-01)

Uncleavable Nup98–Nup96 is functional in the fission yeastSchizosaccharomyces pombe
by: Haruhiko Asakawa, et al.
Published: (2015-01-01)

Cytoplasmic polyadenylation in S. pombe
by: Stevenson, A, et al.
Published: (2005)

Latrunculin A-Induced Perturbation of the Actin Cytoskeleton Mediates Pap1p-Dependent Induction of the Caf5p Efflux Pump in Schizosaccharomyces pombe
by: Farzad Asadi, et al.
Published: (2017-02-01)

Schizosaccharomyces pombe Grx4, Fep1, and Php4: In silico analysis and expression response to different iron concentrations
by: Alia Ebrahim, et al.
Published: (2022-12-01)

A genome-wide analysis of carbon catabolite repression in Schizosaccharomyces pombe
by: Dane Vassiliadis, et al.
Published: (2019-03-01)

The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress
by: Naomi Coulton, et al.
Published: (2017-12-01)

Differences in the Volatile Profile of Apple Cider Fermented with <i>Schizosaccharomyces pombe</i> and <i>Schizosaccharomyces japonicus</i>
by: Nicola Ferremi Leali, et al.
Published: (2024-02-01)

Neuroprotective effect of 6-paradol enriched ginger extract by fermentation using Schizosaccharomyces pombe
by: Ji Won Choi, et al.
Published: (2017-04-01)

The Schizosaccharomyces pombe checkpoint kinases Chk1 and Cds1 are important for cell survival in response to cisplatin.
by: Domenica Paparatto, et al.
Published: (2009-07-01)

Unexpected insertion of carrier DNA sequences into the fission yeast genome during CRISPR–Cas9 mediated gene deletion
by: Sophie Longmuir, et al.
Published: (2019-03-01)

Tell the Difference Between Mitosis and Meiosis: Interplay Between Chromosomes, Cytoskeleton, and Cell Cycle Regulation
by: Masamitsu Sato, et al.
Published: (2021-04-01)

Cytoophidia Influence Cell Cycle and Size in <i>Schizosaccharomyces pombe</i>
by: Ruolan Deng, et al.
Published: (2024-01-01)

Communication between Cyclin-dependent kinase Cdc2 and the Wis1-Spc1 MAPK pathway determines mitotic timing in Schizosaccharomyces pombe
by: Agamani Ghosal, et al.
Published: (2020-07-01)