The comparison of eight different common in vitro and ex vivo environments with in vivo conditions applying model collagen samples: Correlation possibilities and their limits

New biomaterials are routinely evaluated for their degradation behaviour in the real body environment. Following the 3R strategy, in vitro simulated body conditions are often preferred. No studies that simultaneously compare such conditions with the real body environment have been conducted to date....

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Main Authors: Tomáš Suchý, Lucie Vištejnová, Radek Sedláček, Marika Vopálková, Monika Šupová, Gražyna Simha Martynková, Ján Staňo, Pavel Klein, František Denk, Ján Kužma, Martin Bartoš
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Polymer Testing
Online Access:http://www.sciencedirect.com/science/article/pii/S0142941824002988