Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis.

In most sexually reproducing organisms crossing over between chromosome homologs during meiosis is essential to produce haploid gametes. Most crossovers that form in meiosis in budding yeast result from the biased resolution of double Holliday junction (dHJ) intermediates. This dHJ resolution step i...

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Bibliographic Details
Main Authors: Michael Gioia, Lisette Payero, Sagar Salim, Ghanim Fajish V, Amamah F Farnaz, Gianno Pannafino, Jun Jie Chen, V P Ajith, Sherikat Momoh, Michelle Scotland, Vandana Raghavan, Carol M Manhart, Akira Shinohara, K T Nishant, Eric Alani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-04-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002085