A novel loss-of-function variant in PNLDC1 inducing oligo-astheno-teratozoospermia and male infertility

A novel loss-of-function variant in PNLDC1 inducing oligo-astheno-teratozoospermia and male infertility

Male infertility is a major reproductive disorder, which is clinically characterized by highly heterogeneous phenotypes of abnormal sperm count or quality. To date, five male patients with biallelic loss-of-function (LOF) variants of PARN-like ribonuclease domain-containing exonuclease 1 (PNLDC1) ha...

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Bibliographic Details
Main Authors: Si-Yi Zhao, Lan-Lan Meng, Zhao-Li Du, Yue-Qiu Tan, Wen-Bin He, Xiong Wang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Asian Journal of Andrology
Subjects:
loss-of-function variant; male infertility; oligo-astheno-teratozoospermia; parn-like ribonuclease domain-containing exonuclease 1
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=5;spage=643;epage=645;aulast=

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=5;spage=643;epage=645;aulast=

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