Dynamics of Acute Liver Injury in Experimental Models of Hepatotoxicity in the Context of Their Implementation in Preclinical Studies on Stem Cell Therapy

Dynamics of Acute Liver Injury in Experimental Models of Hepatotoxicity in the Context of Their Implementation in Preclinical Studies on Stem Cell Therapy

Background and Aims: Experimental models using carbon tetrachloride (CCl4) and D-galactosamine (D-GalN) can be used in preclinical assessment of acute liver failure (ALF) therapies. Unfortunately, these models are characterized by different dynamics of liver injury depending on the animal strain, ad...

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Bibliographic Details
Main Authors: Piotr Czekaj, Mateusz Król, Łukasz Limanówka, Aleksandra Skubis-Sikora, Emanuel Kolanko, Edyta Bogunia, Mateusz Hermyt, Marcin Michalik, Bartosz Sikora, Agnieszka Prusek, Aniela Grajoszek, Jacek Pająk
Format: Article
Language:English
Published: IMR Press 2022-08-01
Series:Frontiers in Bioscience-Landmark
Subjects:
experimental models of hepatotoxicity
galactosamine
carbon tetrachloride
acute liver failure
stem cell therapy
Online Access:https://www.imrpress.com/journal/FBL/27/8/10.31083/j.fbl2708237

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https://www.imrpress.com/journal/FBL/27/8/10.31083/j.fbl2708237

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