Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors

Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors

The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic ce...

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Bibliographic Details
Main Authors: Thibault E. Schmid, Sammy Drissi-Amraoui, Christophe Crévisy, Olivier Baslé, Marc Mauduit
Format: Article
Language:English
Published: Beilstein-Institut 2015-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
conjugate additions
electron-deficient alkenes
enantioselective catalysis
extended Michael acceptors
organometallic nucleophiles
sequential addition
Online Access:https://doi.org/10.3762/bjoc.11.263

Internet

https://doi.org/10.3762/bjoc.11.263

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