Regulation of Translational Efficiency by Disparate 5′-UTRs of PPARγ Splice Variants

The PPAR-γ gene encodes for at least 7 unique transcripts due to alternative splicing of five exons in the 5′-untranslated region (UTR). The translated region is encoded by exons 1–6, which are identical in all isoforms. This study investigated the role of the 5′-UTR in regulating the efficiency wit...

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Bibliographic Details
Main Authors: Shawn McClelland, Roopali Shrivastava, Jheem D. Medh
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/193413