Single cell profiling at the maternal–fetal interface reveals a deficiency of PD-L1+ non-immune cells in human spontaneous preterm labor

Single cell profiling at the maternal–fetal interface reveals a deficiency of PD-L1+ non-immune cells in human spontaneous preterm labor

Abstract The mechanisms that underlie the timing of labor in humans are largely unknown. In most pregnancies, labor is initiated at term (≥ 37 weeks gestation), but in a signifiicant number of women spontaneous labor occurs preterm and is associated with increased perinatal mortality and morbidity....

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Bibliographic Details
Main Authors: Xiao Liu, Ivy Aneas, Noboru Sakabe, Rebecca L. Anderson, Christine Billstrand, Cristina Paz, Harjot Kaur, Brian Furner, Seong Choi, Adriana Y. Prichina, Elizabeth Ann L. Enninga, Haidong Dong, Amy Murtha, Gregory E. Crawford, John A. Kessler, William Grobman, Marcelo A. Nobrega, Sarosh Rana, Carole Ober
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35051-5

Internet

https://doi.org/10.1038/s41598-023-35051-5

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