Inverse Solvent Isotope Effects in Enzyme-Catalyzed Reactions

Solvent isotope effects have long been used as a mechanistic tool for determining enzyme mechanisms. Most commonly, macroscopic rate constants such as <i>k</i><sub>cat</sub> and <i>k</i><sub>cat</sub>/<i>K</i><sub>m</sub> are fo...

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Bibliographic Details
Main Authors: Patrick L. Fernandez, Andrew S. Murkin
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/8/1933