Vascular biosafety of commercial hydroxyapatite particles: discrepancy between blood compatibility assays and endothelial cell behavior

Abstract Background Vascular homeostasis is ensured by a dynamic interplay involving the endothelium, the platelets and the coagulation system. Thus, the vascular safety of particulate materials must address this integrated system, an approach that has been largely neglected. This work analysed the...

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Bibliographic Details
Main Authors: Catarina Santos, Suzy Turiel, Pedro Sousa Gomes, Elísio Costa, Alice Santos-Silva, Paulo Quadros, José Duarte, Sílvia Battistuzzo, Maria Helena Fernandes
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12951-018-0357-y