Haplotype threading: accurate polyploid phasing from long reads

Haplotype threading: accurate polyploid phasing from long reads

Abstract Resolving genomes at haplotype level is crucial for understanding the evolutionary history of polyploid species and for designing advanced breeding strategies. Polyploid phasing still presents considerable challenges, especially in regions of collapsing haplotypes.We present WhatsHap polyph...

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Bibliographic Details
Main Authors: Sven D. Schrinner, Rebecca Serra Mari, Jana Ebler, Mikko Rautiainen, Lancelot Seillier, Julia J. Reimer, Björn Usadel, Tobias Marschall, Gunnar W. Klau
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Genome Biology
Subjects:
Polyploidy
Phasing
Haplotypes
Cluster editing
High-throughput nucleotide sequencing
Plant science
Online Access:http://link.springer.com/article/10.1186/s13059-020-02158-1

Internet

http://link.springer.com/article/10.1186/s13059-020-02158-1

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