Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression

Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression

Anti-programmed cell death 1 (PD-1) or anti-PD-ligand (L) 1 drugs, as classic immune checkpoint inhibitors, are considered promising treatment strategies for tumors. In clinical practice, some cancer patients experience drug resistance and disease progression in the process of anti-PD-1/PD-L1 immuno...

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Bibliographic Details
Main Authors: Yunzhou Pu, Qing Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint inhibitor (ICI)
PD-1/PD-L1 axis
immunosuppression
tumor-associated macrophages (TAMs)
immune microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.874589/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.874589/full

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