IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells

Abstract Introduction Inflammation plays a significant role in various cancers, including lung cancer, where the inflammatory cytokine IL-1β is often elevated in the tumor microenvironment. Patients with lung adenocarcinoma show higher levels of serum IL-1β compared to healthy individual. Moreover,...

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Bibliographic Details
Main Authors: Afshan Fathima Nawas, Ashley Solmonson, Boning Gao, Ralph J. DeBerardinis, John D. Minna, Maralice Conacci-Sorrell, Carole R. Mendelson
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Cell Communication and Signaling
Online Access:https://doi.org/10.1186/s12964-023-01348-1