Maternal exposure to genistein during pregnancy and oxidative DNA damage in testes of male mouse offspring

Maternal exposure to genistein during pregnancy and oxidative DNA damage in testes of male mouse offspring

BackgroundGenistein is a dietary supplement with phyto-estrogenic properties. Therefore, high intake of genistein during pregnancy may have adverse effects on the genetic integrity of testes and germ cells of male offspring. In this study, we examined whether maternal exposure to genistein during pr...

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Bibliographic Details
Main Authors: Roger W. L. Godschalk, Margit C. M. Janssen, Kimberly Vanhees, Sahar Barjesteh van Waalwijk van Doorn-Khosrovani, Frederik-Jan van Schooten
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Nutrition
Subjects:
genistein
estrogen metabolism
testes
antioxidant system
DNA damage
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2022.904368/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2022.904368/full

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