cGMP Signaling and Vascular Smooth Muscle Cell Plasticity

cGMP Signaling and Vascular Smooth Muscle Cell Plasticity

Cyclic GMP regulates multiple cell types and functions of the cardiovascular system. This review summarizes the effects of cGMP on the growth and survival of vascular smooth muscle cells (VSMCs), which display remarkable phenotypic plasticity during the development of vascular diseases, such as athe...

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Bibliographic Details
Main Authors: Moritz Lehners, Hyazinth Dobrowinski, Susanne Feil, Robert Feil
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
cyclic guanosine 3′-5′ monophosphate
nitric oxide
vascular smooth muscle cells
cGMP-dependent protein kinase type I
atherosclerosis
cell plasticity
transdifferentiation
cell fate mapping
imaging
Online Access:http://www.mdpi.com/2308-3425/5/2/20

Internet

http://www.mdpi.com/2308-3425/5/2/20

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