Porphyromonas gingivalis, a periodontal pathogen, impairs post-infarcted myocardium by inhibiting autophagosome–lysosome fusion

Abstract While several previous studies have indicated the link between periodontal disease (PD) and myocardial infarction (MI), the underlying mechanisms remain unclear. Autophagy, a cellular quality control process that is activated in several diseases, including heart failure, can be suppressed b...

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Bibliographic Details
Main Authors: Yuka Shiheido-Watanabe, Yasuhiro Maejima, Shun Nakagama, Qintao Fan, Natsuko Tamura, Tetsuo Sasano
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-023-00251-2