Nickel-catalyzed enantioselective domino Heck/Sonogashira coupling for construction of C(sp)-C(sp3) bond-substituted quaternary carbon centers
Enantioselective chemical transformations to introduce sp carbons and trifluoromethyl group into 3,3-disubstituted-2-oxindoles is among chemists' most wanted. We report a single nickel-catalyzed enantioselective domino Heck/Sonogashira annulation/alkynylation process to construct an all-carbon...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-06-01
|
| Series: | Tetrahedron Chem |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666951X22000171 |