Using Bayesian adaptive designs to improve phase III trials: a respiratory care example

Using Bayesian adaptive designs to improve phase III trials: a respiratory care example

Abstract Background Bayesian adaptive designs can improve the efficiency of trials, and lead to trials that can produce high quality evidence more quickly, with fewer patients and lower costs than traditional methods. The aim of this work was to determine how Bayesian adaptive designs can be constru...

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Bibliographic Details
Main Authors: Elizabeth G. Ryan, Julie Bruce, Andrew J. Metcalfe, Nigel Stallard, Sarah E. Lamb, Kert Viele, Duncan Young, Simon Gates
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Medical Research Methodology
Subjects:
Bayesian sequential design
Interim analyses
Randomised controlled trials
Critical care
Online Access:http://link.springer.com/article/10.1186/s12874-019-0739-3

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http://link.springer.com/article/10.1186/s12874-019-0739-3

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