SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining
Abstract Background DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mamma...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-06-01
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Series: | Cancer Reports |
Subjects: | |
Online Access: | https://doi.org/10.1002/cnr2.1341 |