SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining

Abstract Background DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mamma...

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Bibliographic Details
Main Authors: Meghana Manjunath, Bibha Choudhary, Sathees C. Raghavan
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Cancer Reports
Subjects:
Online Access:https://doi.org/10.1002/cnr2.1341