Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
Abstract Background Treatment resistant schizophrenia (TRS) is broadly defined as inadequate response to adequate treatment and is associated with a substantial increase in disease burden. Clozapine is the only approved treatment for TRS, showing superior clinical effect on overall symptomatology co...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-09-01
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| Series: | Human Genomics |
| Online Access: | https://doi.org/10.1186/s40246-024-00673-x |