The mitochondrial dysfunction, alongside the modifiable burden of traditional risk factors, drives the development of early-onset coronary artery disease

The mitochondrial dysfunction, alongside the modifiable burden of traditional risk factors, drives the development of early-onset coronary artery disease

ObjectiveMitochondrial dysfunction is associated with increased risk of atherosclerosis by disrupting key cellular processes that contribute to premature vascular ageing. However, the specific role of mitochondrial dysfunction in early-onset coronary artery disease (EOCAD), which is increasing at a...

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Bibliographic Details
Main Authors: Jonica Campolo, Paola Canale, Gianluca Gazzaniga, Marina Parolini, Emanuela Piccaluga, Irene Bossi, Jacopo Oreglia, Andrea Borghini, Irene Marinaro, Maria Grazia Andreassi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
mitochondrial dysfunction
atherosclerosis
premature vascular ageing
early coronary artery disease
mtDNA-CN
mtDNA4977
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1538202/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1538202/full

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