Gastric pH in Rats: Key Determinant for Preclinical Evaluation of pH-dependent Oral Drug Absorption
Data on gastric pH in rats to be used in preclinical models for pH-dependent drug absorption are still limited or contradictory. The aim of this study was to describe gastric pH in rats at fasted state and to evaluate its changes induced by pentagastrin or omeprazole in order to mimic gastric pH at...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karolinum Press
2019-01-01
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Series: | Prague Medical Report |
Subjects: | |
Online Access: | https://pmr.lf1.cuni.cz/120/1/0005/ |