Intrahepatic Tissue Implantation Represents a Favorable Approach for Establishing Orthotopic Transplantation Hepatocellular Carcinoma Mouse Models.

Mouse models are commonly used for studying hepatocellular carcinoma (HCC) biology and exploring new therapeutic interventions. Currently three main modalities of HCC mouse models have been extensively employed in pre-clinical studies including chemically induced, transgenic and transplantation mode...

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Bibliographic Details
Main Authors: Quan Rao, Abin You, Zhenglong Guo, Bingfeng Zuo, Xianjun Gao, Ti Zhang, Zhi Du, Chenxuan Wu, HaiFang Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4732811?pdf=render