Heat shock protein 90β inhibits apoptosis of intestinal epithelial cells induced by hypoxia through stabilizing phosphorylated Akt

Heat shock protein 90β inhibits apoptosis of intestinal epithelial cells induced by hypoxia through stabilizing phosphorylated Akt

Intestinal epithelial cell (IEC) apoptosis induced by hypoxiacompromise intestinal epithelium barrier function. Both Akt andHsp90 have cytoprotective function. However, the specific roleof Akt and Hsp90β in IEC apoptosis induced by hypoxia has notbeen explored. We confirmed that hypoxia-induced apop...

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Bibliographic Details
Main Authors: Shuai Zhang, Yong Sun, Zhiqiang Yuan, Ying Li, Xiaolu Li, Zhenyu Gong, Yizhi Peng
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-01-01
Series:BMB Reports
Subjects:
Apoptosis
Caco2 cells
Hypoxia
Intestinal epithelial cell
PI3K/Akt signaling pathway
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xJTVEMTMwMTI5MjExOF8lMjgwNDctMDUyJTI5Qk1CXzEyLTAzNy5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xJTVEMTMwMTI5MjExOF8lMjgwNDctMDUyJTI5Qk1CXzEyLTAzNy5wZGY=

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