Variation of the human mu-opioid receptor (OPRM1) gene predicts vulnerability to frustration

Abstract Understanding the emotional reaction to loss, or frustration, is a critical problem for the field of mental health. Animal models of loss have pointed to the opioid system as a nexus of frustration, physical pain, and substance abuse. However, few attempts have been made to connect the resu...

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Bibliographic Details
Main Authors: Alan M. Daniel, Brenda G. Rushing, Karla Y. Tapia Menchaca
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78783-4