OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain—a statistical analysis plan

OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain—a statistical analysis plan

Abstract Background Low back and neck pain are a leading cause of disease burden globally. Opioids are recommended in guidelines for acute low back and neck pain; however, there is a lack of compelling efficacy data to support this. Methods The OPAL trial is a prospectively registered, triple-blinde...

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Bibliographic Details
Main Authors: Caitlin MP Jones, Chung-Wei Christine Lin, Richard O. Day, Bart W. Koes, Jane Latimer, Chris G. Maher, Andrew McLachlan, Laurent Billot
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Trials
Subjects:
Opioids
Low back pain
Neck pain
Placebo-controlled trial
Statistical analysis plan
Online Access:https://doi.org/10.1186/s13063-022-06028-y

Internet

https://doi.org/10.1186/s13063-022-06028-y

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