p97 complexes as signal integration hubs

<p>Abstract</p> <p>In the ubiquitin-proteasome system, a subset of ubiquitylated proteins requires the AAA+ ATPase p97 (also known as VCP or Cdc48) for extraction from membranes or protein complexes before delivery to the proteasome for degradation. Diverse ubiquitin adapters are k...

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Bibliographic Details
Main Author: Meyer Hemmo
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/10/48