The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates

The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates

Base excision repair (BER) is one of the important systems for the maintenance of genome stability via repair of DNA lesions. BER is a multistep process involving a number of enzymes, including damage-specific DNA glycosylases, apurinic/apyrimidinic (AP) endonuclease 1, DNA polymerase β, and DNA lig...

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Bibliographic Details
Main Authors: Artemiy S. Bakman, Stanislav S. Boichenko, Aleksandra A. Kuznetsova, Alexander A. Ishchenko, Murat Saparbaev, Nikita A. Kuznetsov
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
DNA repair
apurinic/apyrimidinic endonuclease
DNA–protein interaction
protein–protein interaction
damaged DNA transfer
conformational change
Online Access:https://www.mdpi.com/1422-0067/24/11/9594

Internet

https://www.mdpi.com/1422-0067/24/11/9594

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