Foodborne cereulide causes beta-cell dysfunction and apoptosis.

AIMS/HYPOTHESIS:To study the effects of cereulide, a food toxin often found at low concentrations in take-away meals, on beta-cell survival and function. METHODS:Cell death was quantified by Hoechst/Propidium Iodide in mouse (MIN6) and rat (INS-1E) beta-cell lines, whole mouse islets and control cel...

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Main Authors: Roman Vangoitsenhoven, Dieter Rondas, Inne Crèvecoeur, Wannes D'Hertog, Pieter Baatsen, Matilde Masini, Mirjana Andjelkovic, Joris Van Loco, Christophe Matthys, Chantal Mathieu, Lut Overbergh, Bart Van der Schueren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4132018?pdf=render